AirportFusion

Flights from Panama City to Santa Cruz

Every non-stop option between the Panama City area and the Santa Cruz area: airlines, airport pairs, estimated fares and flight times. Launch a full door-to-door search to add ground transport on both sides, one-stop alternatives and an AI recommendation.

Estimated price

from €391

Flight time

≈ 5h 5m

Distance

3466 km

Airlines

1

Compare door-to-door itineraries

Free — includes trains, taxis and buses to the airports, plus connecting flights.

Airlines flying Panama City → Santa Cruz non-stop

Airport pairs served

RouteAirlinesFlight timeEstimated price
PTY → VVI1≈ 5h 5mfrom €391

Prices are deterministic estimates based on distance, season and airline — final fares come from the booking partner.

Frequently asked questions

Which airlines fly direct from Panama City to Santa Cruz?
1 airline(s) operate non-stop flights between the Panama City area and the Santa Cruz area, including Copa Airlines.
How much does a flight from Panama City to Santa Cruz cost?
Our estimates start at €391 for a one-way non-stop ticket. Real fares vary with the season, the day of the week and how early you book — Tuesdays and Wednesdays are usually cheapest.
How long is the flight from Panama City to Santa Cruz?
The non-stop flight covers about 3466 km and takes approximately 5h 5m, depending on the exact airport pair and winds.
What is the fastest door-to-door option?
It depends on which airports you can reach easily. AirportFusion compares every airport around your exact address — including trains, taxis and buses on both sides — and recommends the best complete itinerary.
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